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Crosstalk between mitochondrial stress signals regulates yeast chronological lifespan

Mitochondrial DNA (mtDNA) exists in multiple copies per cell and is essential for oxidative phosphorylation. Depleted or mutated mtDNA promotes numerous human diseases and may contribute to aging. Reduced TORC1 signaling in the budding yeast, Saccharomyces cerevisiae, extends chronological lifespan...

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Hlavní autoři: Schroeder, Elizabeth A., Shadel, Gerald S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943709/
https://ncbi.nlm.nih.gov/pubmed/24373996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2013.12.002
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