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Caloric Restriction Extends Yeast Chronological Life Span by Optimizing the Snf1 (AMPK) Signaling Pathway

AMP-activated protein kinase (AMPK) and the homologous yeast SNF1 complex are key regulators of energy metabolism that counteract nutrient deficiency and ATP depletion by phosphorylating multiple enzymes and transcription factors that maintain energetic homeostasis. AMPK/SNF1 also promotes longevity...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Wierman, Margaret B., Maqani, Nazif, Strickler, Erika, Li, Mingguang, Smith, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472825/
https://ncbi.nlm.nih.gov/pubmed/28373292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00562-16
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