Caloric Restriction Extends Yeast Chronological Life Span by Optimizing the Snf1 (AMPK) Signaling Pathway

AMP-activated protein kinase (AMPK) and the homologous yeast SNF1 complex are key regulators of energy metabolism that counteract nutrient deficiency and ATP depletion by phosphorylating multiple enzymes and transcription factors that maintain energetic homeostasis. AMPK/SNF1 also promotes longevity...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Wierman, Margaret B., Maqani, Nazif, Strickler, Erika, Li, Mingguang, Smith, Jeffrey S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5472825/
https://ncbi.nlm.nih.gov/pubmed/28373292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00562-16
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