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Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H(2)O(2) and superoxide dismutase activity

The free radical theory of aging posits oxidative damage to macromolecules as a primary determinant of lifespan. Recent studies challenge this theory by demonstrating that in some cases, longevity is enhanced by inactivation of oxidative stress defenses or is correlated with increased, rather than d...

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Autors principals: Mesquita, Ana, Weinberger, Martin, Silva, Alexandra, Sampaio-Marques, Belém, Almeida, Bruno, Leão, Cecília, Costa, Vítor, Rodrigues, Fernando, Burhans, William C., Ludovico, Paula
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930563/
https://ncbi.nlm.nih.gov/pubmed/20696905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004432107
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