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A cell-nonautonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism

Caloric restriction (CR) improves health span and life span of organisms ranging from yeast to mammals. Understanding the mechanisms involved will uncover future interventions for aging-associated diseases. In budding yeast, Saccharomyces cerevisiae, CR is commonly defined by reduced glucose in the...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Enriquez-Hesles, Elisa, Smith, Daniel L., Maqani, Nazif, Wierman, Margaret B., Sutcliffe, Matthew D., Fine, Ryan D., Kalita, Agata, Santos, Sean M., Muehlbauer, Michael J., Bain, James R., Janes, Kevin A., Hartman, John L., Hirschey, Matthew D., Smith, Jeffrey S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7949035/
https://ncbi.nlm.nih.gov/pubmed/33243834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015402
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