Structure-Activity Relationships of Different β-Lactam Antibiotics against a Soluble Form of Enterococcus faecium PBP5, a Type II Bacterial Transpeptidase

Penicillin-binding proteins (PBPs) catalyze the essential reactions in the biosynthesis of cell wall peptidoglycan from glycopeptide precursors. β-Lactam antibiotics normally interfere with this process by reacting covalently with the active site serine to form a stable acyl-enzyme. The design of no...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Hujer, Andrea M., Kania, Malgosia, Gerken, Thomas, Anderson, Vernon E., Buynak, John D., Ge, Xiaoxia, Caspers, Patrick, Page, Malcolm G. P., Rice, Louis B., Bonomo, Robert A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC547200/
https://ncbi.nlm.nih.gov/pubmed/15673741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.2.612-618.2005
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares