Impact of Specific pbp5 Mutations on Expression of β-Lactam Resistance in Enterococcus faecium

We tested the impact of individual PBP 5 mutations on expression of ampicillin resistance in Enterococcus faecium using a shuttle plasmid designed to facilitate expression of cloned pbp5 in ampicillin-susceptible E. faecium D344SRF. Substitutions that had been implicated in contributing to the resis...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Rice, Louis B., Bellais, Samuel, Carias, Lenore L., Hutton-Thomas, Rebecca, Bonomo, Robert A., Caspers, Patrick, Page, Malcolm G. P., Gutmann, Laurent
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2004
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC478487/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15273117/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.8.3028-3032.2004
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