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Activity of Ceftaroline against Enterococcus faecium PBP5
The opportunistic human pathogen Enterococcus faecium overproduces the low-affinity PBP5. In clinical strains, mutations in PBP5 further reduce its acylation rate by β-lactams. Previous studies have reported that ceftaroline had poor inhibitory activity against β-lactam-resistant E. faecium strains....
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3837919/ https://ncbi.nlm.nih.gov/pubmed/24060866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00923-13 |
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