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Characterization of DNA substrate binding to the phosphatase domain of the DNA repair enzyme, PNKP
Polynucleotide kinase/phosphatase (PNKP) is a DNA strand break repair enzyme that uses separate 5′ kinase and 3′ phosphatase active sites to convert damaged 5′-hydroxyl/3′-phosphate strand termini to ligatable 5′-phosphate/3′-hydroxyl ends. The phosphatase active site has received particular attenti...
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| 出版年: | Biochemistry |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5469602/ https://ncbi.nlm.nih.gov/pubmed/28276686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01236 |
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