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Characterization of DNA substrate binding to the phosphatase domain of the DNA repair enzyme, PNKP

Polynucleotide kinase/phosphatase (PNKP) is a DNA strand break repair enzyme that uses separate 5′ kinase and 3′ phosphatase active sites to convert damaged 5′-hydroxyl/3′-phosphate strand termini to ligatable 5′-phosphate/3′-hydroxyl ends. The phosphatase active site has received particular attenti...

詳細記述

保存先:
書誌詳細
出版年:Biochemistry
主要な著者: Havali-Shahriari, Zahra, Weinfeld, Michael, Mark Glover, J. N.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469602/
https://ncbi.nlm.nih.gov/pubmed/28276686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01236
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