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Tidying up loose ends: the role of polynucleotide kinase/phosphatase in DNA strand break repair

The termini of DNA strand breaks induced by internal and external factors often require processing before missing nucleotides can be replaced by DNA polymerases and the strands rejoined by DNA ligases. Polynucleotide kinase/phosphatase (PNKP) serves a critical role in the repair of DNA strand breaks...

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Detalhes bibliográficos
Main Authors: Weinfeld, Michael, Mani, Rajam S., Abdou, Ismail, Acetuno, R. Daniel, Glover, J.N. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134258/
https://ncbi.nlm.nih.gov/pubmed/21353781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2011.01.006
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