Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology

Proteins implicated in neurodegenerative conditions such as Alzheimer’s disease (AD) and Dementia with Lewy Bodies (DLB) have been identified in bodily fluids encased in extracellular vesicles called exosomes. Whether exosomes found in DLB patients can transmit pathology is not clear. In this study,...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Ngolab, Jennifer, Trinh, Ivy, Rockenstein, Edward, Mante, Michael, Florio, Jazmin, Trejo, Margarita, Masliah, Deborah, Adame, Anthony, Masliah, Eliezer, Rissman, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466770/
https://ncbi.nlm.nih.gov/pubmed/28599681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0445-5
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