Longitudinal live imaging of retinal α-synuclein::GFP deposits in a transgenic mouse model of Parkinson’s Disease/Dementia with Lewy Bodies

Abnormal α-synuclein (α-syn) accumulation in the CNS may underlie neuronal cell and synaptic dysfunction leading to motor and cognitive deficits in synucleinopathies including Parkinson’s disease (PD) and Dementia with Lewy Bodies (DLB). Multiple groups demonstrated α-syn accumulation in CNS accesso...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Price, Diana L., Rockenstein, Edward, Mante, Michael, Adame, Anthony, Overk, Cassia, Spencer, Brian, Duong-Polk, Karen X., Bonhaus, Douglas, Lindsey, James, Masliah, Eliezer
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937425/
https://ncbi.nlm.nih.gov/pubmed/27389831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29523
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