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Longitudinal live imaging of retinal α-synuclein::GFP deposits in a transgenic mouse model of Parkinson’s Disease/Dementia with Lewy Bodies

Abnormal α-synuclein (α-syn) accumulation in the CNS may underlie neuronal cell and synaptic dysfunction leading to motor and cognitive deficits in synucleinopathies including Parkinson’s disease (PD) and Dementia with Lewy Bodies (DLB). Multiple groups demonstrated α-syn accumulation in CNS accesso...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Price, Diana L., Rockenstein, Edward, Mante, Michael, Adame, Anthony, Overk, Cassia, Spencer, Brian, Duong-Polk, Karen X., Bonhaus, Douglas, Lindsey, James, Masliah, Eliezer
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937425/
https://ncbi.nlm.nih.gov/pubmed/27389831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29523
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