Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology

Proteins implicated in neurodegenerative conditions such as Alzheimer’s disease (AD) and Dementia with Lewy Bodies (DLB) have been identified in bodily fluids encased in extracellular vesicles called exosomes. Whether exosomes found in DLB patients can transmit pathology is not clear. In this study,...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol Commun
Main Authors: Ngolab, Jennifer, Trinh, Ivy, Rockenstein, Edward, Mante, Michael, Florio, Jazmin, Trejo, Margarita, Masliah, Deborah, Adame, Anthony, Masliah, Eliezer, Rissman, Robert A.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466770/
https://ncbi.nlm.nih.gov/pubmed/28599681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0445-5
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