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Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology

Proteins implicated in neurodegenerative conditions such as Alzheimer’s disease (AD) and Dementia with Lewy Bodies (DLB) have been identified in bodily fluids encased in extracellular vesicles called exosomes. Whether exosomes found in DLB patients can transmit pathology is not clear. In this study,...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Acta Neuropathol Commun
Prif Awduron: Ngolab, Jennifer, Trinh, Ivy, Rockenstein, Edward, Mante, Michael, Florio, Jazmin, Trejo, Margarita, Masliah, Deborah, Adame, Anthony, Masliah, Eliezer, Rissman, Robert A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466770/
https://ncbi.nlm.nih.gov/pubmed/28599681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-017-0445-5
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