α‐synuclein conformational antibodies fused to penetratin are effective in models of Lewy body disease

OBJECTIVE: Progressive accumulation of α‐synuclein (α‐syn) has been associated with Parkinson's disease (PD) and Dementia with Lewy body (DLB). The mechanisms through which α‐syn leads to neurodegeneration are not completely clear; however, the formation of various oligomeric species have been...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Spencer, Brian, Williams, Stephanie, Rockenstein, Edward, Valera, Elvira, Xin, Wei, Mante, Michael, Florio, Jazmin, Adame, Anthony, Masliah, Eliezer, Sierks, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4999592/
https://ncbi.nlm.nih.gov/pubmed/27606342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.321
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