Monoglyceride lipase deficiency affects hepatic cholesterol metabolism and lipid-dependent gut transit in ApoE−/− mice

Monoglyceride lipase (MGL) hydrolyzes monoglycerides (MGs) to glycerol and fatty acids. Among various MG species MGL also degrades 2-arachidonoylglycerol (2-AG), the most abundant endocannabinoid and potent activator of cannabinoid receptors (CBR) 1 and 2. MGL-knockout (−/−) mice exhibit pronounced...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Vujic, Nemanja, Korbelius, Melanie, Leopold, Christina, Duta-Mare, Madalina, Rainer, Silvia, Schlager, Stefanie, Goeritzer, Madeleine, Kolb, Dagmar, Eichmann, Thomas O., Diwoky, Clemens, Zimmer, Andreas, Zimmermann, Robert, Lass, Achim, Radovic, Branislav, Kratky, Dagmar
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464855/
https://ncbi.nlm.nih.gov/pubmed/28380440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16529
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