Monoglyceride lipase deficiency modulates endocannabinoid signaling and improves plaque stability in ApoE-knockout mice

BACKGROUND AND AIMS: Monoglyceride lipase (MGL) catalyzes the final step of lipolysis by degrading monoglyceride (MG) to glycerol and fatty acid. MGL also hydrolyzes and thereby deactivates 2-arachidonoyl glycerol (2-AG), the most abundant endocannabinoid in the mammalian system. 2-AG acts as full a...

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Publicado no:Atherosclerosis
Main Authors: Vujic, Nemanja, Schlager, Stefanie, Eichmann, Thomas O., Madreiter-Sokolowski, Corina T., Goeritzer, Madeleine, Rainer, Silvia, Schauer, Silvia, Rosenberger, Angelika, Woelfler, Albert, Doddapattar, Prakash, Zimmermann, Robert, Hoefler, Gerald, Lass, Achim, Graier, Wolfgang F., Radovic, Branislav, Kratky, Dagmar
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704137/
https://ncbi.nlm.nih.gov/pubmed/26584135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2015.10.109
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