Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis

In humans, mutations in ATGL lead to TG accumulation in LDs of most tissues and cells, including peripheral blood leukocytes. This pathologic condition is called Jordans’ anomaly, in which functional consequences have not been investigated. In the present study, we tested the hypothesis that ATGL pl...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Schlager, Stefanie, Goeritzer, Madeleine, Jandl, Katharina, Frei, Robert, Vujic, Nemanja, Kolb, Dagmar, Strohmaier, Heimo, Dorow, Juliane, Eichmann, Thomas O., Rosenberger, Angelika, Wölfler, Albert, Lass, Achim, Kershaw, Erin E., Ceglarek, Uta, Dichlberger, Andrea, Heinemann, Akos, Kratky, Dagmar
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2015
Assuntos:
Inflammation, Extracellular Mediators, & Effector Molecules
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594763/
https://ncbi.nlm.nih.gov/pubmed/26109679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0515-206R
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