Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis

In humans, mutations in ATGL lead to TG accumulation in LDs of most tissues and cells, including peripheral blood leukocytes. This pathologic condition is called Jordans’ anomaly, in which functional consequences have not been investigated. In the present study, we tested the hypothesis that ATGL pl...

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Dades bibliogràfiques
Publicat a:J Leukoc Biol
Autors principals: Schlager, Stefanie, Goeritzer, Madeleine, Jandl, Katharina, Frei, Robert, Vujic, Nemanja, Kolb, Dagmar, Strohmaier, Heimo, Dorow, Juliane, Eichmann, Thomas O., Rosenberger, Angelika, Wölfler, Albert, Lass, Achim, Kershaw, Erin E., Ceglarek, Uta, Dichlberger, Andrea, Heinemann, Akos, Kratky, Dagmar
Format: Artigo
Idioma:Inglês
Publicat: Society for Leukocyte Biology 2015
Matèries:
Inflammation, Extracellular Mediators, & Effector Molecules
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594763/
https://ncbi.nlm.nih.gov/pubmed/26109679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0515-206R
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