Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis

In humans, mutations in ATGL lead to TG accumulation in LDs of most tissues and cells, including peripheral blood leukocytes. This pathologic condition is called Jordans’ anomaly, in which functional consequences have not been investigated. In the present study, we tested the hypothesis that ATGL pl...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:J Leukoc Biol
Autori principali: Schlager, Stefanie, Goeritzer, Madeleine, Jandl, Katharina, Frei, Robert, Vujic, Nemanja, Kolb, Dagmar, Strohmaier, Heimo, Dorow, Juliane, Eichmann, Thomas O., Rosenberger, Angelika, Wölfler, Albert, Lass, Achim, Kershaw, Erin E., Ceglarek, Uta, Dichlberger, Andrea, Heinemann, Akos, Kratky, Dagmar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Leukocyte Biology 2015
Soggetti:
Inflammation, Extracellular Mediators, & Effector Molecules
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594763/
https://ncbi.nlm.nih.gov/pubmed/26109679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0515-206R
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