Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis

In humans, mutations in ATGL lead to TG accumulation in LDs of most tissues and cells, including peripheral blood leukocytes. This pathologic condition is called Jordans’ anomaly, in which functional consequences have not been investigated. In the present study, we tested the hypothesis that ATGL pl...

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Bibliografische gegevens
Gepubliceerd in:J Leukoc Biol
Hoofdauteurs: Schlager, Stefanie, Goeritzer, Madeleine, Jandl, Katharina, Frei, Robert, Vujic, Nemanja, Kolb, Dagmar, Strohmaier, Heimo, Dorow, Juliane, Eichmann, Thomas O., Rosenberger, Angelika, Wölfler, Albert, Lass, Achim, Kershaw, Erin E., Ceglarek, Uta, Dichlberger, Andrea, Heinemann, Akos, Kratky, Dagmar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Leukocyte Biology 2015
Onderwerpen:
Inflammation, Extracellular Mediators, & Effector Molecules
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594763/
https://ncbi.nlm.nih.gov/pubmed/26109679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0515-206R
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