טוען...
Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis
Lysosomal acid lipase (LAL) is the only known enzyme, which hydrolyzes cholesteryl esters and triacylglycerols in lysosomes of multiple cells and tissues. Here, we explored the role of LAL in brown adipose tissue (BAT). LAL-deficient (Lal-/-) mice exhibit markedly reduced UCP1 expression in BAT, mod...
שמור ב:
| הוצא לאור ב: | Biochim Biophys Acta |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5839464/ https://ncbi.nlm.nih.gov/pubmed/29374543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2018.01.011 |
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