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Intestine-specific DGAT1 deficiency improves atherosclerosis in apolipoprotein E knockout mice by reducing systemic cholesterol burden
BACKGROUND AND AIMS: Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) is the rate-limiting enzyme catalyzing the final step of triglyceride synthesis by esterifying a diglyceride with a fatty acid. We have previously shown that apolipoprotein E-knockout (ApoE (−/−)) mice lacking Dgat1 have reduced...
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| Publicat a: | Atherosclerosis |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7116265/ https://ncbi.nlm.nih.gov/pubmed/32882484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2020.07.030 |
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