Lysosomal acid lipase regulates fatty acid channeling in brown adipose tissue to maintain thermogenesis

Lysosomal acid lipase (LAL) is the only known enzyme, which hydrolyzes cholesteryl esters and triacylglycerols in lysosomes of multiple cells and tissues. Here, we explored the role of LAL in brown adipose tissue (BAT). LAL-deficient (Lal-/-) mice exhibit markedly reduced UCP1 expression in BAT, mod...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Duta-Mare, Madalina, Sachdev, Vinay, Leopold, Christina, Kolb, Dagmar, Vujic, Nemanja, Korbelius, Melanie, Hofer, Dina C., Xia, Wenmin, Huber, Katharina, Auer, Martina, Gottschalk, Benjamin, Magnes, Christoph, Graier, Wolfgang F., Prokesch, Andreas, Radovic, Branislav, Bogner-Strauss, Juliane G., Kratky, Dagmar
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5839464/
https://ncbi.nlm.nih.gov/pubmed/29374543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2018.01.011
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados