SIRT1 Regulates HIV Transcription via Tat Deacetylation

The human immunodeficiency virus (HIV) Tat protein is acetylated by the transcriptional coactivator p300, a necessary step in Tat-mediated transactivation. We report here that Tat is deacetylated by human sirtuin 1 (SIRT1), a nicotinamide adenine dinucleotide-dependent class III protein deacetylase...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Pagans, Sara, Pedal, Angelika, North, Brian J, Kaehlcke, Katrin, Marshall, Brett L, Dorr, Alexander, Hetzer-Egger, Claudia, Henklein, Peter, Frye, Roy, McBurney, Michael W, Hruby, Henning, Jung, Manfred, Verdin, Eric, Ott, Melanie
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2005
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC546329/
https://ncbi.nlm.nih.gov/pubmed/15719057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0030041
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker