The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide–dependent deacetylase

The yeast silent information regulator (Sir)2 protein links cellular metabolism and transcriptional silencing through its nicotinamide adenine dinucleotide (NAD)-dependent histone deacetylase activity. We report that mitochondria from mammalian cells contain intrinsic NAD-dependent deacetylase activ...

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Autori principali: Schwer, Björn, North, Brian J., Frye, Roy A., Ott, Melanie, Verdin, Eric
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2002
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174009/
https://ncbi.nlm.nih.gov/pubmed/12186850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200205057
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