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The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide–dependent deacetylase

The yeast silent information regulator (Sir)2 protein links cellular metabolism and transcriptional silencing through its nicotinamide adenine dinucleotide (NAD)-dependent histone deacetylase activity. We report that mitochondria from mammalian cells contain intrinsic NAD-dependent deacetylase activ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schwer, Björn, North, Brian J., Frye, Roy A., Ott, Melanie, Verdin, Eric
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174009/
https://ncbi.nlm.nih.gov/pubmed/12186850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200205057
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