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Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses
Certain RGD-binding integrins are required for cell adhesion, migration, and proliferation and are overexpressed in most tumors, making them attractive therapeutic targets. However, multiple integrin antagonist drug candidates have failed to show efficacy in cancer clinical trials. In this work, we...
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| 出版年: | J Exp Med |
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| 主要な著者: | , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5460993/ https://ncbi.nlm.nih.gov/pubmed/28473400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160831 |
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