USP13 negatively regulates antiviral responses by deubiquitinating STING

STING (also known as MITA) is critical for host defence against viruses and the activity of STING is regulated by ubiquitination. However, the deubiquitination of STING is not fully understood. Here, we show that ubiquitin-specific protease 13 (USP13) is a STING-interacting protein that catalyses de...

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Publicat a:Nat Commun
Autors principals: Sun, He, Zhang, Qiang, Jing, Ying-Ying, Zhang, Man, Wang, Hai-Ying, Cai, Zeng, Liuyu, Tianzi, Zhang, Zhi-Dong, Xiong, Tian-Chen, Wu, Yan, Zhu, Qi-Yun, Yao, Jing, Shu, Hong-Bing, Lin, Dandan, Zhong, Bo
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457515/
https://ncbi.nlm.nih.gov/pubmed/28534493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15534
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