Clinical Activity of the γ-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis)

PURPOSE: Desmoid tumors (aggressive fibromatosis) arise from connective tissue cells or fibroblasts. In general, they are slow growing and do not metastasize; however, locally aggressive desmoid tumors can cause severe morbidity and loss of function. Disease recurrence after surgery and/or radiation...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Clin Oncol
Main Authors: Kummar, Shivaani, O'Sullivan Coyne, Geraldine, Do, Khanh T., Turkbey, Baris, Meltzer, Paul S., Polley, Eric, Choyke, Peter L., Meehan, Robert, Vilimas, Rasa, Horneffer, Yvonne, Juwara, Lamin, Lih, Ann, Choudhary, Amul, Mitchell, Sandra A., Helman, Lee J., Doroshow, James H., Chen, Alice P.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Clinical Oncology 2017
נושאים:
Original Reports
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455706/
https://ncbi.nlm.nih.gov/pubmed/28350521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.71.1994
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