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Clinical Activity of the γ-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis)

PURPOSE: Desmoid tumors (aggressive fibromatosis) arise from connective tissue cells or fibroblasts. In general, they are slow growing and do not metastasize; however, locally aggressive desmoid tumors can cause severe morbidity and loss of function. Disease recurrence after surgery and/or radiation...

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Bibliografski detalji
Izdano u:J Clin Oncol
Glavni autori: Kummar, Shivaani, O'Sullivan Coyne, Geraldine, Do, Khanh T., Turkbey, Baris, Meltzer, Paul S., Polley, Eric, Choyke, Peter L., Meehan, Robert, Vilimas, Rasa, Horneffer, Yvonne, Juwara, Lamin, Lih, Ann, Choudhary, Amul, Mitchell, Sandra A., Helman, Lee J., Doroshow, James H., Chen, Alice P.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Clinical Oncology 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455706/
https://ncbi.nlm.nih.gov/pubmed/28350521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.71.1994
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