Clinical Activity of the γ-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis)

PURPOSE: Desmoid tumors (aggressive fibromatosis) arise from connective tissue cells or fibroblasts. In general, they are slow growing and do not metastasize; however, locally aggressive desmoid tumors can cause severe morbidity and loss of function. Disease recurrence after surgery and/or radiation...

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Detaylı Bibliyografya
Yayımlandı:J Clin Oncol
Asıl Yazarlar: Kummar, Shivaani, O'Sullivan Coyne, Geraldine, Do, Khanh T., Turkbey, Baris, Meltzer, Paul S., Polley, Eric, Choyke, Peter L., Meehan, Robert, Vilimas, Rasa, Horneffer, Yvonne, Juwara, Lamin, Lih, Ann, Choudhary, Amul, Mitchell, Sandra A., Helman, Lee J., Doroshow, James H., Chen, Alice P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Clinical Oncology 2017
Konular:
Original Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455706/
https://ncbi.nlm.nih.gov/pubmed/28350521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.71.1994
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