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Clinical Activity of the γ-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors (Aggressive Fibromatosis)

PURPOSE: Desmoid tumors (aggressive fibromatosis) arise from connective tissue cells or fibroblasts. In general, they are slow growing and do not metastasize; however, locally aggressive desmoid tumors can cause severe morbidity and loss of function. Disease recurrence after surgery and/or radiation...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Kummar, Shivaani, O'Sullivan Coyne, Geraldine, Do, Khanh T., Turkbey, Baris, Meltzer, Paul S., Polley, Eric, Choyke, Peter L., Meehan, Robert, Vilimas, Rasa, Horneffer, Yvonne, Juwara, Lamin, Lih, Ann, Choudhary, Amul, Mitchell, Sandra A., Helman, Lee J., Doroshow, James H., Chen, Alice P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455706/
https://ncbi.nlm.nih.gov/pubmed/28350521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.71.1994
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