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Osteopontin Deficiency Suppresses Intestinal Tumor Development in Apc-Deficient Min Mice
Osteopontin (OPN) is a secreted phosphoglycoprotein, and is a transcriptional target of aberrant Wnt signaling. OPN is upregulated in human colon cancers, and is suggested to enhance cancer progression. In this study, the effect of deficiency of OPN on intestinal tumor development in Apc-deficient M...
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| Pubblicato in: | Int J Mol Sci |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5454970/ https://ncbi.nlm.nih.gov/pubmed/28505114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18051058 |
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