Osteopontin Deficiency Suppresses Intestinal Tumor Development in Apc-Deficient Min Mice

Osteopontin (OPN) is a secreted phosphoglycoprotein, and is a transcriptional target of aberrant Wnt signaling. OPN is upregulated in human colon cancers, and is suggested to enhance cancer progression. In this study, the effect of deficiency of OPN on intestinal tumor development in Apc-deficient M...

Full description

Saved in:
Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Ishigamori, Rikako, Komiya, Masami, Takasu, Shinji, Mutoh, Michihiro, Imai, Toshio, Takahashi, Mami
Format: Artigo
Language:Inglês
Published: MDPI 2017
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454970/
https://ncbi.nlm.nih.gov/pubmed/28505114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18051058
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items