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Osteopontin Deficiency Suppresses Intestinal Tumor Development in Apc-Deficient Min Mice

Osteopontin (OPN) is a secreted phosphoglycoprotein, and is a transcriptional target of aberrant Wnt signaling. OPN is upregulated in human colon cancers, and is suggested to enhance cancer progression. In this study, the effect of deficiency of OPN on intestinal tumor development in Apc-deficient M...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Ishigamori, Rikako, Komiya, Masami, Takasu, Shinji, Mutoh, Michihiro, Imai, Toshio, Takahashi, Mami
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454970/
https://ncbi.nlm.nih.gov/pubmed/28505114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18051058
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