Suppressive effects of the NADPH oxidase inhibitor apocynin on intestinal tumorigenesis in obese KK‐A (y) and Apc mutant Min mice

Obesity is a risk factor for colorectal cancer. The accumulation of abdominal fat tissue causes abundant reactive oxygen species production through the activation of NADPH oxidase due to excessive insulin stimulation. The enzyme NADPH oxidase catalyzes the production of reactive oxygen species and e...

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Veröffentlicht in:Cancer Sci
Hauptverfasser: Komiya, Masami, Fujii, Gen, Miyamoto, Shingo, Takahashi, Mami, Ishigamori, Rikako, Onuma, Wakana, Ishino, Kousuke, Totsuka, Yukari, Fujimoto, Kyoko, Mutoh, Michihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2015
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714685/
https://ncbi.nlm.nih.gov/pubmed/26310859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12801
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