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Suppressive effects of the NADPH oxidase inhibitor apocynin on intestinal tumorigenesis in obese KK‐A (y) and Apc mutant Min mice

Obesity is a risk factor for colorectal cancer. The accumulation of abdominal fat tissue causes abundant reactive oxygen species production through the activation of NADPH oxidase due to excessive insulin stimulation. The enzyme NADPH oxidase catalyzes the production of reactive oxygen species and e...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Komiya, Masami, Fujii, Gen, Miyamoto, Shingo, Takahashi, Mami, Ishigamori, Rikako, Onuma, Wakana, Ishino, Kousuke, Totsuka, Yukari, Fujimoto, Kyoko, Mutoh, Michihiro
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714685/
https://ncbi.nlm.nih.gov/pubmed/26310859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12801
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