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3D-QSAR, Molecular Docking and Molecular Dynamics Simulation of Pseudomonas aeruginosa LpxC Inhibitors

As an important target for the development of novel antibiotics, UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC) has been widely studied. Pyridone methylsulfone hydroxamate (PMH) compounds can effectively inhibit the catalytic activity of LpxC. In this work, the three-dimension...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Mol Sci
Egile Nagusiak: Zuo, Ke, Liang, Li, Du, Wenyi, Sun, Xin, Liu, Wei, Gou, Xiaojun, Wan, Hua, Hu, Jianping
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454807/
https://ncbi.nlm.nih.gov/pubmed/28481250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18050761
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