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Tristetraprolin expression by keratinocytes controls local and systemic inflammation
Tristetraprolin (TTP, encoded by the Zfp36 gene) regulates the mRNA stability of several important cytokines. Due to the critical role of this RNA-binding protein in the control of inflammation, TTP deficiency leads to the spontaneous development of a complex inflammatory syndrome. So far, this phen...
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Publicado no: | JCI Insight |
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Main Authors: | , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5453703/ https://ncbi.nlm.nih.gov/pubmed/28570274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92979 |
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