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Tristetraprolin (TTP) as a Therapeutic Target in Inflammatory Disease
Members of the tristetraprolin (TTP) family of RNA binding proteins are found in all major eukaryotic groups. Family members from plants through humans can bind AU-rich elements in target mRNAs with high affinity. In mammalian cells, these proteins then promote deadenylation and decay of target tran...
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發表在: | Trends Pharmacol Sci |
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Main Authors: | , |
格式: | Artigo |
語言: | Inglês |
出版: |
2016
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5030171/ https://ncbi.nlm.nih.gov/pubmed/27503556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2016.07.002 |
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