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Tristetraprolin (TTP) as a Therapeutic Target in Inflammatory Disease

Members of the tristetraprolin (TTP) family of RNA binding proteins are found in all major eukaryotic groups. Family members from plants through humans can bind AU-rich elements in target mRNAs with high affinity. In mammalian cells, these proteins then promote deadenylation and decay of target tran...

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Detalhes bibliográficos
Publicado no:Trends Pharmacol Sci
Main Authors: Patial, Sonika, Blackshear, Perry J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030171/
https://ncbi.nlm.nih.gov/pubmed/27503556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2016.07.002
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