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Tristetraprolin (TTP) as a Therapeutic Target in Inflammatory Disease

Members of the tristetraprolin (TTP) family of RNA binding proteins are found in all major eukaryotic groups. Family members from plants through humans can bind AU-rich elements in target mRNAs with high affinity. In mammalian cells, these proteins then promote deadenylation and decay of target tran...

詳細記述

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書誌詳細
出版年:Trends Pharmacol Sci
主要な著者: Patial, Sonika, Blackshear, Perry J.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5030171/
https://ncbi.nlm.nih.gov/pubmed/27503556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2016.07.002
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