Enhanced stability of tristetraprolin mRNA protects mice against immune-mediated inflammatory pathologies

Tristetraprolin (TTP) is an inducible, tandem zinc-finger mRNA binding protein that binds to adenylate-uridylate–rich elements (AREs) in the 3′-untranslated regions (3′UTRs) of specific mRNAs, such as that encoding TNF, and increases their rates of deadenylation and turnover. Stabilization of Tnf mR...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Patial, Sonika, Curtis, Alan D., Lai, Wi S., Stumpo, Deborah J., Hill, Georgette D., Flake, Gordon P., Mannie, Mark D., Blackshear, Perry J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763790/
https://ncbi.nlm.nih.gov/pubmed/26831084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519906113
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados