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Stimulation of Polo-Like Kinase 3 mRNA Decay by Tristetraprolin

Polo-like protein kinase 3 (Plk3) has been proposed to regulate entry into S phase and promote apoptosis in response to oxidative stress. Its mRNA contains three AU-rich elements (AREs) in its 3′ untranslated region (3′-UTR) that can contribute to the rapid degradation of labile transcripts. We inve...

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Hlavní autoři: Horner, Thierry J., Lai, Wi S., Stumpo, Deborah J., Blackshear, Perry J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663294/
https://ncbi.nlm.nih.gov/pubmed/19188452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00982-08
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