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Tristetraprolin (TTP): Interactions with mRNA and proteins, and current thoughts on mechanisms of action

Changes in mRNA stability and translation are critical control points in the regulation of gene expression, particularly genes encoding growth factors, inflammatory mediators, and proto-oncogenes. Adenosine and uridine (AU)-rich elements (ARE), often located in the 3′ untranslated regions (3′UTR) of...

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Detalles Bibliográficos
Main Authors: Brooks, Seth A., Blackshear, Perry J.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752887/
https://ncbi.nlm.nih.gov/pubmed/23428348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2013.02.003
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