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Tristetraprolin (TTP): Interactions with mRNA and proteins, and current thoughts on mechanisms of action

Changes in mRNA stability and translation are critical control points in the regulation of gene expression, particularly genes encoding growth factors, inflammatory mediators, and proto-oncogenes. Adenosine and uridine (AU)-rich elements (ARE), often located in the 3′ untranslated regions (3′UTR) of...

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Dettagli Bibliografici
Autori principali: Brooks, Seth A., Blackshear, Perry J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752887/
https://ncbi.nlm.nih.gov/pubmed/23428348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2013.02.003
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