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Tristetraprolin (TTP): Interactions with mRNA and proteins, and current thoughts on mechanisms of action

Changes in mRNA stability and translation are critical control points in the regulation of gene expression, particularly genes encoding growth factors, inflammatory mediators, and proto-oncogenes. Adenosine and uridine (AU)-rich elements (ARE), often located in the 3′ untranslated regions (3′UTR) of...

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書誌詳細
主要な著者: Brooks, Seth A., Blackshear, Perry J.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752887/
https://ncbi.nlm.nih.gov/pubmed/23428348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2013.02.003
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