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Tristetraprolin (TTP): Interactions with mRNA and proteins, and current thoughts on mechanisms of action

Changes in mRNA stability and translation are critical control points in the regulation of gene expression, particularly genes encoding growth factors, inflammatory mediators, and proto-oncogenes. Adenosine and uridine (AU)-rich elements (ARE), often located in the 3′ untranslated regions (3′UTR) of...

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Detalhes bibliográficos
Main Authors: Brooks, Seth A., Blackshear, Perry J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752887/
https://ncbi.nlm.nih.gov/pubmed/23428348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2013.02.003
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