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Tristetraprolin expression by keratinocytes controls local and systemic inflammation
Tristetraprolin (TTP, encoded by the Zfp36 gene) regulates the mRNA stability of several important cytokines. Due to the critical role of this RNA-binding protein in the control of inflammation, TTP deficiency leads to the spontaneous development of a complex inflammatory syndrome. So far, this phen...
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| 出版年: | JCI Insight |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5453703/ https://ncbi.nlm.nih.gov/pubmed/28570274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92979 |
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