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Tristetraprolin expression by keratinocytes controls local and systemic inflammation

Tristetraprolin (TTP, encoded by the Zfp36 gene) regulates the mRNA stability of several important cytokines. Due to the critical role of this RNA-binding protein in the control of inflammation, TTP deficiency leads to the spontaneous development of a complex inflammatory syndrome. So far, this phen...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Andrianne, Mathieu, Assabban, Assiya, La, Caroline, Mogilenko, Denis, Salle, Delphine Staumont, Fleury, Sébastien, Doumont, Gilles, Van Simaeys, Gaëtan, Nedospasov, Sergei A., Blackshear, Perry J., Dombrowicz, David, Goriely, Stanislas, Van Maele, Laurye
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5453703/
https://ncbi.nlm.nih.gov/pubmed/28570274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92979
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