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Decreased Sensitivity of Tristetraprolin-deficient Cells to p38 Inhibitors Suggests the Involvement of Tristetraprolin in the p38 Signaling Pathway

Treatment of macrophages with pyridinyl imidazole inhibitors of p38 protein kinases can inhibit lipopolysaccharide-stimulated tumor necrosis factor α secretion. However, bone marrow-derived macrophages from tristetraprolin (TTP)-deficient mice were less sensitive than normal macrophages to this effe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Carballo, Ester, Cao, Heping, Lai, Wi S., Kennington, Elizabeth A., Campbell, Douglas, Blackshear, Perry J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351389/
https://ncbi.nlm.nih.gov/pubmed/11546803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M104953200
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