Lataa...
Lysosome-oriented, dual-stage pH-responsive polymeric micelles for β-Lapachone delivery
β-Lapachone (β-lap), a novel anticancer agent, is bioactivated by NADP(H):quinone oxidoreductase 1 (NQO1), an enzyme over-expressed in numerous tumors, including lung, pancreas, breast, and prostate cancers. Fast renal clearance and methemaglobinemia / hemolytic side-effects from the clinical formul...
Tallennettuna:
| Julkaisussa: | J Mater Chem B Mater Biol Med |
|---|---|
| Päätekijät: | , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2016
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5452003/ https://ncbi.nlm.nih.gov/pubmed/28580145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C6TB02049F |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|