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HDAC8 Prevents Anthrax Lethal Toxin-induced Cell Cycle Arrest through Silencing PTEN in Human Monocytic THP-1 Cells

Anthrax lethal toxin (LeTx) is a cytotoxic virulence factor that causes cell cycle arrest and cell death in various cell types. However, susceptibility to the cytotoxic effects varies depending on cell types. In proliferating monocytes, LeTx has only transient cytotoxic effects due to activation of...

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Dettagli Bibliografici
Pubblicato in:Toxins (Basel)
Autori principali: Ha, Soon-Duck, Cho, Woohyun, Kim, Sung Ouk
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450710/
https://ncbi.nlm.nih.gov/pubmed/28509866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9050162
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